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SKETCHY MICRO CMV SERIAL
SKETCHY MICRO CMV SKIN

Transplacental transmission occurs following primary infection of a seronegative mother during pregnancy. Cesarean delivery if lesions are present at delivery.Localized CNS involvement: meningoencephalitis.Skin, eyes, and mouth involvement: vesicular lesions, keratoconjunctivitis.Second immunization of mother after delivery if serologic titers remain negative.Petechiae and purpura ( blueberry muffin rash).Heart defects (e.g., PDA, pulmonary artery stenosis).Avoid potentially contaminated workplaces (e.g., schools, pediatric clinics).Intrauterine fetal blood transfusion if indicated.

SKETCHY MICRO CMV SERIAL

Serial ultrasounds to rule out fetal hydrops.

Active immunization of mother before pregnancy.

Varicella-zoster immune globulin ( VZIG).

Avoidance of unpasteurized dairy products.

SKETCHY MICRO CMV SKIN

Vesicular and pustular skin lesions ( granulomatosis infantiseptica ).

Spontaneous abortion and premature birth.

Early congenital syphilis (onset 2 years).

Immediate administration of spiramycin to prevent of fetal toxoplasmosis.

Pyrimethamine, sulfadiazine, and folinic acid.

Petechiae and purpu ra ( blueberry muffin rash).

Diffuse intracranial calcifications ( ring-enhancing lesions ).

During pregnancy : may cause intrauterine fetal demise and miscarriage.

Others (e.g., syphilis, varicella, parvovirus B19 infection, listeriosis).

Overview DescriptionĬongenital TORCH infections are vertically transmitted infections (acquired directly from the mother and transmitted to the embryo, fetus, or newborn through the placenta or birth canal) that are capable of significantly influencing fetal and neonatal morbidity and mortality The pathogens are discussed in more detail in their respective articles. coli, gonococcal infections and chlamydial infections, West Nile virus, Zika virus, measles virus, enterovirus, and adenovirus. These include HIV in pregnancy, perinatal hepatitis B, group B streptococci, E. Several other pathogens can also be vertically transmitted during pregnancy and have detrimental effects on the fetus and/or newborn. Affected infants require regular follow-ups to monitor for hearing loss, ophthalmological abnormalities, and developmental delays. Primary prevention includes vaccination for varicella and rubella (prior to pregnancy), hygiene measures (washing hands and avoiding certain foods), and screening for syphilis during pregnancy. Prophylaxis is of great importance during pregnancy. These infections can also cause abnormalities in the CNS, the skeletal and endocrine systems, and the complex organs (e.g., cardiac defects, vision and hearing loss). TORCH infections can cause spontaneous abortion, premature birth, and intrauterine growth restriction ( IUGR).

The acronym TORCH stands for the causative pathogens of congenital infections: Toxoplasma gondii, others (including Treponema pallidum, Listeria, varicella zoster virus, and parvovirus B19), rubella virus, cytomegalovirus ( CMV), and herpes simplex virus ( HSV). They can have a substantial negative impact on fetal and neonatal health. Congenital infections are caused by pathogens transmitted from mother to child during pregnancy (transplacentally) or delivery (peripartum).